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What are FG beads?
FG beads, specially designed for Receptor Fishing, are magnetic nanoparticles originally developed by the researchers in Professor Handa’s laboratory at the Tokyo Institute of Technology in Japan. The beads are readily separable and recoverable by a magnet. The bead, which is 200 nm in diameter, has several ferrite particles in its core, and is covered with poly-GMA (Glycidyl methacrylate)(Figure 1). Since the bead contains epoxy groups originating from the GMA on its surface, ligands can be readily connected.
SG beads (first-generation nanoparticles initially developed by Professor Handa, Tokyo Institute of Technology) have delivered useful experimental results in Receptor Fishing to improve the quality of the beads. FG beads are second-generation nanoparticles with the same superior characteristics as SG beads, and are magnetically separable.
【 Structure of SG Beads and FG Beads 】
